•Avène RetrinAL 0.05 Cream visibly reduces appearance of deep wrinkles and furrows while smoothing and renewing skin. Formulated with innovative physician-strength Vitamin A (Retinal) that is clinically proven to be more effective than Retinol without irritating the skin*, for a youthful, radiant look. •*Edwards. Topical Retinol and Retinaldehyde in cosmetics as alternatives to Retinoic Acid evidence of efficacy. Retinoids 2001; Volume 17 Number 4. •Avène's Retrinal collection is a clinically advanced pro-aging skincare line powered by physician-strength Retinal (Retinaldehyde) that visibly corrects signs of aging. •Skin appears plump and firm, bright and luminous for a youthful appearance.